Taking Ziprasidone during pregnancy, allergy warnings

Features questions and information about Ziprasidone structure, pregnancy & Ziprasidone allergy warnings. What should I ask before taking Ziprasidone .

Ziprasidone is not for use in psychotic conditions that are related to dementia. Ziprasidone has caused fatal heart attack and pneumonia in older adults with dementia-related conditions.

Do not use this medication if you are allergic to ziprasidone, or if you have:

  • a personal or family history of "Long QT syndrome"
  • history of recent heart attack; or
  • uncontrolled or untreated heart failure

Ziprasidone should never be taken together with any of the following drugs, or a life-threatening heart rhythm disorder could occur:

  • arsenic trioxide (Trisenox)
  • dolasetron (Anzemet)
  • droperidol (Inapsine)
  • halofantrine (Halfan)
  • mefloquine (Lariam)
  • levomethadyl acetate (no longer available in the U.S.)
  • tacrolimus (Prograf)
  • antibiotics such as gatifloxacin (Tequin), pentamidine (NebuPent, Pentam), moxifloxacin (Avelox), sparfloxacin (Zagam), telithromycin (Ketek)
  • heart rhythm medicine such as dofetilide (Tikosyn), disopyramide (Norpace), quinidine (Cardioquin, Quinaglute), or sotalol (Betapace); or
  • medicines to treat psychiatric disorders, such as chlorpromazine (Thorazine), mesoridazine (Serentil), pimozide (Orap), or thioridazine (Mellaril)

Before taking ziprasidone, tell your doctor if you are allergic to any drugs, or if you have:

  • a heart rhythm disorder
  • a history of heart attack or stroke
  • low blood levels of potassium or magnesium
  • diabetes (ziprasidone may raise your blood sugar)
  • seizures or epilepsy
  • a history of suicidal thoughts
  • Parkinson's disease, Alzheimer's
  • trouble swallowing
  • liver disease; or
  • kidney disease

If you have any of these conditions, you may need a dose adjustment or special tests to safely take ziprasidone.

Ziprasidone may cause you to have high blood sugar (hyperglycemia). Talk to your doctor if you have any signs of hyperglycemia such as increased thirst or urination, excessive hunger, or weakness. If you are diabetic, check your blood sugar levels on a regular basis while you are taking ziprasidone.

The ziprasidone orally disintegrating tablet may contain phenylalanine. Talk to your doctor before using this form of ziprasidone if you have phenylketonuria (PKU).

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether ziprasidone passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Older adults may be more likely to have side effects from this medicine.

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