Zicam Sinus Relief (Oxymetazoline Nasal) interactions

Includes Zicam Sinus Relief interactions, drugs that can interact with Zicam Sinus Relief. What other drugs can affect Oxymetazoline Nasal, Zicam Sinus Relief interaction.




Do not use oxymetazoline nasal if you have taken a monoamine oxidase (MAO) inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days.

Although drug interactions between topical nasal decongestants and drugs taken by mouth are not expected, they can occur. Rarely, oxymetazoline nasal may interact with the following medicines:

  • furazolidone (Furoxone)
  • guanethidine (Ismelin)
  • indomethacin (Indocin)
  • methyldopa (Aldomet)
  • bromocriptine (Parlodel)
  • caffeine in cola, tea, coffee, chocolate and other products
  • theophylline (Theo-Dur, Theochron, Theolair, others)
  • tricyclic antidepressants such as amitriptyline (Elavil, Endep), doxepin (Sinequan), and nortriptyline (Pamelor)
  • other commonly used tricyclic antidepressants, including amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), imipramine (Tofranil), protriptyline (Vivactil), and trimipramine (Surmontil)
  • phenothiazines such as chlorpromazine (Thorazine), thioridazine (Mellaril), and prochlorperazine (Compazine); and
  • other commonly used phenothiazines, including fluphenazine (Prolixin), perphenazine (Trilafon), mesoridazine (Serentil), and trifluoperazine (Stelazine)

Drugs other than those listed here may also interact with oxymetazoline nasal. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.











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