Sodium Phenylbutyrate side effects, toxicity

What are the possible Sodium Phenylbutyrate side effects, liver and heart possible problems, Sodium Phenylbutyrate toxicity and allergic reactions, side effects.




Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using sodium phenylbutyrate and call your doctor at once if you have any of these serious side effects:

Call your doctor at once if you have a serious side effect such as:

  • fast, slow, or uneven heart rate
  • swelling, rapid weight gain
  • feeling like you might pass out; or
  • changes in mood, personality, or behavior

Less serious side effects may include:

  • changes in menstrual periods
  • loss of appetite
  • headache
  • increased body odor
  • unusual or unpleasant taste in your mouth

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

Even with treatment, urea cycle disorders can cause a build-up of ammonia in the blood which can result in life-threatening side effects. Seek emergency medical attention if notice any signs of ammonia build-up, including mood or behavior changes, memory loss, thinking problems, muscle twitching, back and forth movement of the eyes, vomiting, increasing weakness, slurred speech, seizure (convulsions), and fainting.











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