Oxaliplatin side effects, toxicity

What are the possible Oxaliplatin side effects, liver and heart possible problems, Oxaliplatin toxicity and allergic reactions, side effects.

Some people receiving a oxaliplatin injection have had a reaction to the infusion within minutes after the medicine is injected into the vein. Tell your caregiver right away if you feel short of breath, confused, sweaty, itchy, or have diarrhea, chest pain, warmth or redness in your face, or feel like you might pass out.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • numbness or tingly feeling in your hands, feet, throat, and around your mouth
  • numbness or burning pain that interferes with daily activities
  • increased sensitivity to cold temperatures and cold objects
  • jaw or chest tightness, eye pain, strange feeling in your tongue, problems with speech or swallowing
  • fever, diarrhea, vomiting, chills, body aches, flu symptoms, sudden cough
  • increased thirst, dry mouth, urinating less than usual
  • easy bruising or bleeding, unusual weakness; or
  • white patches or sores inside your mouth or on your lips

Less serious side effects may include:

  • nausea, stomach pain, loss of appetite
  • diarrhea, constipation
  • tired feeling
  • hair loss
  • decreased taste sensation
  • muscle pain
  • headache
  • sleep problems (insomnia)
  • swelling; or
  • back pain

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

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