The price rating is based on the medium wholesale price for Letairis (Ambrisentan) . The medium wholesale price is the recommended selling price. Insurance companies often use this price as the basis for Letairis (Ambrisentan) reimbursement. This cost does not indicate what you would pay for Letairis (Ambrisentan) if covered by your prescription benefit plan. Dollar signs are used to reflect the following price ranges: $ = < $25, $$ = $25 to $49, $$$ = $50 to $99, $$$$ = $100 to $199, and $$$$$ = > $200.