Lepirudin side effects, toxicity

What are the possible Lepirudin side effects, liver and heart possible problems, Lepirudin toxicity and allergic reactions, side effects.




Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • sudden numbness or weakness, especially on one side of the body
  • sudden headache, confusion, problems with vision, speech, or balance
  • pain or swelling in one or both legs
  • any bleeding that will not stop
  • black, bloody, or tarry stools
  • coughing up blood or vomit that looks like coffee grounds
  • increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure)
  • decreased blood pressure (feeling light-headed or fainting); or
  • urinating less than usual or not at all

Less serious side effects are more likely to occur, such as:

  • pain in your back or pelvis
  • nausea, vomiting, stomach pain or upset
  • feeling restless or nervous
  • headache
  • fever
  • sleep problems (insomnia); or
  • pain, bleeding, or irritation where the injection was given

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.











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