Taking Estro-Span 40 (Estradiol) during pregnancy, allergy warnings

Features questions and information about Estro-Span 40 structure, Estradiol pregnancy & Estro-Span 40 allergy warnings. What should I ask before taking Estro-Span 40 Estradiol.




Do not use estradiol injection if you have:

  • a bleeding or blood-clotting disorder
  • a history of stroke or circulation problems
  • abnormal vaginal bleeding that a doctor has not checked; or
  • any type of breast, uterine, or hormone-dependent cancer

Before using estradiol injection, tell your doctor if you have:

  • high blood pressure, angina, or heart disease
  • high cholesterol or triglycerides
  • liver disease
  • kidney disease
  • asthma
  • epilepsy or other seizure disorder
  • migraines
  • diabetes
  • depression
  • gallbladder disease; or
  • if you have had your uterus removed (hysterectomy)

If you have any of these conditions, you may need a dose adjustment or special tests to safely use estradiol injection.

Estradiol increases your risk of developing endometrial hyperplasia, a condition that may lead to cancer of the uterus. Taking progestins while using estradiol may lower this risk. If your uterus has not been removed, your doctor may prescribe a progestin for you to take while you are using estradiol injection.

Long-term estradiol treatment may increase your risk of stroke. Talk with your doctor about your individual risks before using estradiol long-term. Your doctor should check your progress on a regular basis (every 3 to 6 months) to determine whether you should continue this treatment.

FDA pregnancy category X. This medication can cause birth defects. Do not use estradiol injection if you are pregnant. Tell your doctor right away if you become pregnant during treatment. Use an effective form of birth control while you are using this medication.

Estradiol can pass into breast milk and may harm a nursing baby. This medication may also slow breast milk production. Do not use if you are breast-feeding a baby.











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