Estradiol Levonorgestrel side effects, toxicity

What are the possible Estradiol Levonorgestrel side effects, liver and heart possible problems, Estradiol Levonorgestrel toxicity and allergic reactions, side effects.




Stop using this medication and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of the following serious side effects:

  • signs of a blood clot (sharp chest pain, coughing up blood, shortness of breath, pain in your calf)
  • signs of a heart attack (crushing chest pain, left-arm numbness)
  • signs of a stroke (sudden severe headache, problems with vision or speech, weakness, numbness)
  • nausea, stomach pain, low fever, lost appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or
  • new or changing breast lumps

Other less serious side effects are more likely to occur, such as:

  • nausea and vomiting
  • tender or swollen breasts
  • swelling of the hands or feet
  • darkened spots on the skin of your face
  • contact lens discomfort
  • vaginal irritation or discomfort
  • headache, depressed mood
  • a skin rash or reaction where the patch is worn; or
  • changes in your menstrual periods

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.











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